{"id":4446,"date":"2020-08-04T19:40:51","date_gmt":"2020-08-04T17:40:51","guid":{"rendered":"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/"},"modified":"2021-04-25T18:55:11","modified_gmt":"2021-04-25T16:55:11","slug":"clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients","status":"publish","type":"pubblicazione","link":"https:\/\/www.agingproject.uniupo.it\/en\/research\/publications\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/","title":{"rendered":"Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients"},"content":{"rendered":"

The SARS-Cov-2 pandemic significantly impacted on oncology practice across the globe. There is uncertainty as to the contribution of patients’ demographics and oncological features on severity and mortality from Covid-19 and little guidance as to the role of anti-cancer and anti-Covid-19 therapy in this population. In a multi-center study of 890 cancer patients with confirmed Covid-19 we demonstrated a worsening gradient of mortality from breast cancer to haematological malignancies and showed that male gender, older age, and number of co-morbidities identifies a subset of patients with significantly worse mortality rates from Covid-19. Provision of chemotherapy, targeted therapy and immunotherapy did not worsen mortality. Exposure to antimalarials was associated with improved mortality rates independent of baseline prognostic factors. This study highlights the clinical utility of demographic factors for individualized risk-stratification of patients and support further research into emerging anti-Covid-19 therapeutics in SARS-Cov-2 infected cancer patients.<\/p>\n","protected":false},"template":"","categoria-pubblicazioni":[5056],"class_list":["post-4446","pubblicazione","type-pubblicazione","status-publish","hentry","categoria-pubblicazioni-onco-aging"],"yoast_head":"\nClinical portrait of the SARS-CoV-2 epidemic in European cancer patients | Aging Project Uniupo<\/title>\n<meta name=\"description\" content=\"Covid-19 is lethal for about one in three cancer patients, the danger is increased by gender (male), age (over 65), presence of other diseases.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients\" \/>\n<meta property=\"og:description\" content=\"Covid-19 is lethal for about one in three cancer patients, the danger is increased by gender (male), age (over 65), presence of other diseases.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/\" \/>\n<meta property=\"og:site_name\" content=\"Aging Project Uniupo\" \/>\n<meta property=\"article:modified_time\" content=\"2021-04-25T16:55:11+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@ProjectAging\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/\",\"url\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/\",\"name\":\"Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients | Aging Project Uniupo\",\"isPartOf\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#website\"},\"datePublished\":\"2020-08-04T17:40:51+00:00\",\"dateModified\":\"2021-04-25T16:55:11+00:00\",\"description\":\"Covid-19 is lethal for about one in three cancer patients, the danger is increased by gender (male), age (over 65), presence of other diseases.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/clinical-portrait-of-the-sars-cov-2-epidemic-in-european-cancer-patients\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.agingproject.uniupo.it\/homepage\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pubblicazioni\",\"item\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#website\",\"url\":\"https:\/\/www.agingproject.uniupo.it\/\",\"name\":\"Aging Project Uniupo\",\"description\":\"Facing the challenge of longevity, through interdisciplinary research\",\"publisher\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.agingproject.uniupo.it\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#organization\",\"name\":\"Aging Project - 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