{"id":8945,"date":"2021-09-15T12:15:46","date_gmt":"2021-09-15T10:15:46","guid":{"rendered":"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/"},"modified":"2022-11-01T10:20:49","modified_gmt":"2022-11-01T09:20:49","slug":"lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging","status":"publish","type":"pubblicazione","link":"https:\/\/www.agingproject.uniupo.it\/en\/research\/publications\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/","title":{"rendered":"Lipoic acid, vitamin D3 and their use in preventing brain aging"},"content":{"rendered":"

Context<\/h3>\n

Lipoic acid and vitamin D3 act alone to improve brain aging, since they counteract the main negative effects reported by aging theory. These molecules are able to act like antioxidants, preventing the mitochondrial imbalance and oxidative conditions. In addition, they are able to modulate the inflammation under oxidative conditions preventing neuronal cell loss and activating the survival mechanisms.<\/p>\n

Aim<\/h3>\n

This chapter explores the effects of lipoic acid and vitamin D3 alone to improve brain aging and the effects of their combination, since when they are added together, these effects were amplified.<\/p>\n

Conclusion<\/h3>\n

For the first time Lipoic acid and vitamin D3 may be used to modulate the markers of brain aging and to restore the physiological condition of astrocytes, which is the first cell loss during aging. Since brain aging is a worldwide condition and the use of food supplement is increased, lipoic acid and vitamin D3 are also prepared in a full combination with other molecules in order to obtain a new food supplement able to act in a complete manner on the brain. This combination will be tested also in humans.<\/p>\n","protected":false},"template":"","categoria-pubblicazioni":[5053],"class_list":["post-8945","pubblicazione","type-pubblicazione","status-publish","hentry","categoria-pubblicazioni-modesthe"],"yoast_head":"\nLipoic acid, vitamin D3 and their use in preventing brain aging | Aging Project Uniupo<\/title>\n<meta name=\"description\" content=\"Investigation on the effects of lipoic acid and vitamin D3 alone to improve brain aging, and the effects of their combination.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lipoic acid, vitamin D3 and their use in preventing brain aging\" \/>\n<meta property=\"og:description\" content=\"Investigation on the effects of lipoic acid and vitamin D3 alone to improve brain aging, and the effects of their combination.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/\" \/>\n<meta property=\"og:site_name\" content=\"Aging Project Uniupo\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-01T09:20:49+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@ProjectAging\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/\",\"url\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/\",\"name\":\"Lipoic acid, vitamin D3 and their use in preventing brain aging | Aging Project Uniupo\",\"isPartOf\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#website\"},\"datePublished\":\"2021-09-15T10:15:46+00:00\",\"dateModified\":\"2022-11-01T09:20:49+00:00\",\"description\":\"Investigation on the effects of lipoic acid and vitamin D3 alone to improve brain aging, and the effects of their combination.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/lipoic-acid-vitamin-d3-and-their-use-in-preventing-brain-aging\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.agingproject.uniupo.it\/homepage\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pubblicazioni\",\"item\":\"https:\/\/www.agingproject.uniupo.it\/la-ricerca\/pubblicazioni\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Lipoic acid, vitamin D3 and their use in preventing brain aging\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#website\",\"url\":\"https:\/\/www.agingproject.uniupo.it\/\",\"name\":\"Aging Project Uniupo\",\"description\":\"Facing the challenge of longevity, through interdisciplinary research\",\"publisher\":{\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.agingproject.uniupo.it\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.agingproject.uniupo.it\/#organization\",\"name\":\"Aging Project - 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