Scadenza: 30 November 2021
Topic:
The Call intends to support basic research projects focused on the study of genes / gene families, proteins and RNA molecules whose function is unknown1 in the context of rare2 diseases, of genetic3 and non-genetic origin.
Projects eligible for the Call: focus on the following themes
Genetic aspects:
- genes associated with rare diseases whose function is completely or largely unknown
- one genotype, multiple clinical phenotypes
- variants of uncertain or unknown meaning (VUS)
- genetic modifiers.
Molecular mechanisms:
- folding, stability and degradation of proteins
-metabolism
- inflammatory response
- post-transcriptional and post-translational mechanisms affecting gene function and / or expression and which are responsible for different clinical phenotypes for the same disease.
Ente finanziatore:
Fondazione Cariplo e Fondazione Telethon
Budget complessivo:
Max 250.000 €
Who can participate:
Both projects presented by a single organization and partnership projects can participate in the Call. The organizations, leader and partner, must be Italian non-profit, public or private research bodies.
Researchers who have ongoing funding from the two Foundations can also apply to the Call, while researchers affiliated with the research institutes of Telethon (TIGET, TIGEM and DTI) are not eligible.
Partnership: Not Mandatory
Status:
Closed
Topic:
The Call intends to support basic research projects focused on the study of genes / gene families, proteins and RNA molecules whose function is unknown1 in the context of rare2 diseases, of genetic3 and non-genetic origin.
Projects eligible for the Call: focus on the following themes
Genetic aspects:
- genes associated with rare diseases whose function is completely or largely unknown
- one genotype, multiple clinical phenotypes
- variants of uncertain or unknown meaning (VUS)
- genetic modifiers.
Molecular mechanisms:
- folding, stability and degradation of proteins
-metabolism
- inflammatory response
- post-transcriptional and post-translational mechanisms affecting gene function and / or expression and which are responsible for different clinical phenotypes for the same disease.
Who can participate:
Both projects presented by a single organization and partnership projects can participate in the Call. The organizations, leader and partner, must be Italian non-profit, public or private research bodies.
Researchers who have ongoing funding from the two Foundations can also apply to the Call, while researchers affiliated with the research institutes of Telethon (TIGET, TIGEM and DTI) are not eligible.
Programme:
Consortium: Not required
Status: Open
Total budget:
Max 250.000 €
Funding rate:
Notes:
The text of the Call and the respective guidelines will be available on the websites of the Foundations starting from the end of September 2021.
Call opening: by mid-October 2021 - Forms available on the Telethon portal (http://projects.telethon.it).
Deadline for submitting the application: by the end of November 2021.
